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FAA Civil Aerospace Medical Institute

FAA, Civil Aerospace Medical Institute (CAMI), Aerospace Medical and Human Factors Research. This collection contains reports and resources from the Federal Aviation Administration’s Civil Aerospace Medical Institute (CAMI) aerospace medical and human factors research program. Additional information on this program may be found at https://www.faa.gov/data_research/research/med_humanfacs/. Bookmark this collection:https://rosap.ntl.bts.gov/collection_cami or https://doi.org/10.21949/1530825.

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Identification and Quantification of 22 Benzodiazepines in Postmortem Fluids and Tissues Using UPLC/MS/MS

CITE Title : Identification and Quantification of 22 Benzodiazepines in Postmortem Fluids and Tissues Using UPLC/MS/MS Creator(s) : Angier, Michael K.;Saenz, Sunday R.;Ritter, Roxane M.;Lewis, Russell J.; Corporate Creator(s) : United States. Department of Transportation. Federal Aviation Administration. Office of Aviation. Civil Aerospace Medical Institute Corporate Contributor(s) : United States. Department of Transportation. Federal Aviation Administration. Office of Aviation. Office of Aerospace Medicine Published Date : 2018-05-01 Report Number : DOT/FAA/AM-18/01 URL : /view/dot/57204 "Identification and Quantification of" (2018). "Identification and Quantification of 22 Benzodiazepines in Postmortem Fluids and Tissues Using UPLC/MS/MS" (2018) "Identification and Quantification of 22 Benzodiazepines in Postmortem Fluids and Tissues Using UPLC/MS/MS" , 2018 Export RIS Citation Information.

:

Angier, Michael K. ;

Saenz, Sunday R.

2018-05-01

:

Benzodiazepines, a class of drugs known to cause central nervous system depression, are widely prescribed for a variety of different medical condition...
Postmortem Fluid and Tissue Concentrations of THC, 11-OH-THC, and THC-COOH

CITE Title : Postmortem Fluid and Tissue Concentrations of THC, 11-OH-THC, and THC-COOH Creator(s) : Angier, Mike K.;Wagner, Jarrad R.;Saenz, Sunday R.;Lewis, Russell J.; Corporate Creator(s) : United States. Federal Aviation Administration. Office of Aviation Medicine;Oklahoma State University; Published Date : 2017-04-01 Report Number : DOT/FAA/AM-17/12 URL : /view/dot/37341 "Postmortem Fluid and Tissue" (2017). "Postmortem Fluid and Tissue Concentrations of THC, 11-OH-THC, and THC-COOH" (2017) "Postmortem Fluid and Tissue Concentrations of THC, 11-OH-THC, and THC-COOH" , 2017 Export RIS Citation Information.

:

Angier, Mike K. ;

Wagner, Jarrad R.

2017-04-01

:

Marijuana is the most commonly abused illicit drug worldwide. Marijuana is used for its euphoric and relaxing properties. However, marijuana use has b...
Novel Method for the Determination of Sildenafil (Viagra) and Its Metabolite (UK-103,320) in Postmortem Specimens Using LC/MS/MS and LC/MS/MS/MS.

CITE Title : Novel Method for the Determination of Sildenafil (Viagra) and Its Metabolite (UK-103,320) in Postmortem Specimens Using LC/MS/MS and LC/MS/MS/MS. Creator(s) : Lewis, R. J.;Johnson, R. D.;Blank, C. L.; Corporate Contributor(s) : Civil Aerospace Medical Institute;University of Oklahoma. Dept. of Chemistry and Biochemistry;United States. Office of Aviation Medicine; Published Date : 2000-05-01 Report Number : DOT/FAA/AM-00/20 URL : /view/dot/15398 "Novel Method for the" (2000). "Novel Method for the Determination of Sildenafil (Viagra) and Its Metabolite (UK-103,320) in Postmortem Specimens Using LC/MS/MS and LC/MS/MS/MS." (2000) "Novel Method for the Determination of Sildenafil (Viagra) and Its Metabolite (UK-103,320) in Postmortem Specimens Using LC/MS/MS and LC/MS/MS/MS." , 2000 Export RIS Citation Information.

:

Lewis, R. J. ;

Johnson, R. D.

2000-05-01

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During the investigation of aviation accidents, postmortem samples from victims are submitted to the FAA’sCivil Aeromedical Institute for drug analy...
The Identification and Quantitation of Triamterene in Blood and Urine from a Fatal Aircraft Accident

CITE Title : The Identification and Quantitation of Triamterene in Blood and Urine from a Fatal Aircraft Accident Creator(s) : White, Vicky;Canfield, Dennis V.;Hordinsky, Jerry R.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1992-07-01 Report Number : DOT/FAA/AM-92/23 URL : /view/dot/21391 "The Identification and Quantitation" (1992). "The Identification and Quantitation of Triamterene in Blood and Urine from a Fatal Aircraft Accident" (1992) "The Identification and Quantitation of Triamterene in Blood and Urine from a Fatal Aircraft Accident" , 1992 Export RIS Citation Information.

:

White, Vicky ;

Canfield, Dennis V.

1992-07-01

:

Triamterene, a diuretic drug used in combination with other drugs for the treatment of hypertension, was found in the blood and urine of a fatal aircr...
Tolerance of Beta Blocked Hypertensives during Orthostatic and Altitude Stress

CITE Title : Tolerance of Beta Blocked Hypertensives during Orthostatic and Altitude Stress Creator(s) : Teague, Steven M.;Hordinsky, Jerry R.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1992-04-01 Report Number : DOT/FAA/AM-92/19 URL : /view/dot/21384 "Tolerance of Beta Blocked" (1992). "Tolerance of Beta Blocked Hypertensives during Orthostatic and Altitude Stress" (1992) "Tolerance of Beta Blocked Hypertensives during Orthostatic and Altitude Stress" , 1992 Export RIS Citation Information.

:

Teague, Steven M. ;

Hordinsky, Jerry R.

1992-04-01

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To evaluate the effects of orthostatic, altitude, and pharmacologic stresses upon civil aviation-specific performance, a double-blind, randomized, cro...
Effects of Sleep Loss on Vestibular Response during Simple and Complex Vestibular Stimulation

CITE Title : Effects of Sleep Loss on Vestibular Response during Simple and Complex Vestibular Stimulation Creator(s) : Collins, William E. Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1986-07-01 Report Number : DOT/FAA/AM-86/9 URL : /view/dot/21293 "Effects of Sleep Loss" (1986). "Effects of Sleep Loss on Vestibular Response during Simple and Complex Vestibular Stimulation" (1986) "Effects of Sleep Loss on Vestibular Response during Simple and Complex Vestibular Stimulation" , 1986 Export RIS Citation Information.

:

Collins, William E.

1986-07-01

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Few data are available concerning the effects of sleep loss on vestibular responses although those responses are significant products of motion in avi...
Some effects of smoking withdrawal on complex performance and physiological responses.

CITE Title : Some effects of smoking withdrawal on complex performance and physiological responses. Creator(s) : Mertens, Henry W.;McKenzie, Jess M.;Higgins, E. Arnold; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1983-01-01 Report Number : FAA-AM-83-4;DOT/FAA/AM-83/4; URL : /view/dot/21229 "Some effects of smoking" (1983). "Some effects of smoking withdrawal on complex performance and physiological responses." (1983) "Some effects of smoking withdrawal on complex performance and physiological responses." , 1983 Export RIS Citation Information.

:

Mertens, Henry W. ;

McKenzie, Jess M.

1983-01-01

:

The effects of smoking withdrawal on complex (time-shared) performance and physiological responses were studied at a simulated aircraft cabin altitude...
Effects of some motion sickness suppressants on tracking performance during angular accelerations.

CITE Title : Effects of some motion sickness suppressants on tracking performance during angular accelerations. Creator(s) : Schroeder, David J.;Collins, William E.;Elam, Gary W.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1982-10-01 Report Number : FAA-AM-82-19;DOT/FAA/AM-82/19; URL : /view/dot/21223 "Effects of some motion" (1982). "Effects of some motion sickness suppressants on tracking performance during angular accelerations." (1982) "Effects of some motion sickness suppressants on tracking performance during angular accelerations." , 1982 Export RIS Citation Information.

:

Schroeder, David J. ;

Collins, William E.

1982-10-01

:

The two studies reported here examined the influence of three established antimotion sickness drugs on tracking performance in static (stationary) and...
A comparison of some effects of three antimotion sickness drugs on nystagmic responses to angular accelerations and to optokinetic stimuli.

CITE Title : A comparison of some effects of three antimotion sickness drugs on nystagmic responses to angular accelerations and to optokinetic stimuli. Creator(s) : Collins, William E.;Schroeder, David J.;Elam, Gary W.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1981-08-01 Report Number : FAA-AM-81-16;DOT/FAA/AM-81/16; URL : /view/dot/21197 "A comparison of some" (1981). "A comparison of some effects of three antimotion sickness drugs on nystagmic responses to angular accelerations and to optokinetic stimuli." (1981) "A comparison of some effects of three antimotion sickness drugs on nystagmic responses to angular accelerations and to optokinetic stimuli." , 1981 Export RIS Citation Information.

:

Collins, William E. ;

Schroeder, David J.

1981-08-01

:

This study examined the influence of three established antimotion sickness drugs on nystagmic eye movement responses to angular acceleration (whole-bo...
The effects of tobacco on aviation safety.

CITE Title : The effects of tobacco on aviation safety. Creator(s) : Dille, J.R.;Linder, M.K.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1980-08-01 Report Number : FAA-AM-80-11;DOT/FAA/AM-80/11; URL : /view/dot/21239 "The effects of tobacco" (1980). "The effects of tobacco on aviation safety." (1980) "The effects of tobacco on aviation safety." , 1980 Export RIS Citation Information.

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Dille, J.R. ;

Linder, M.K.

1980-08-01

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In 1976, the FAA was petitioned to issue regulations that would prohibit all smoking in the cockpit during commercial flight operations and prohibit p...
Changes in the oxygen-hemoglobin dissociation curve and time of useful function at hypobaric pressures in rats after chronic oral administration of propranolol.

CITE Title : Changes in the oxygen-hemoglobin dissociation curve and time of useful function at hypobaric pressures in rats after chronic oral administration of propranolol. Creator(s) : McKenzie, J.M.;Higgins, E.A.;Funkhouser, G.E.;Moses, R.;Fowler, P.R.;Wicks, S.M.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1980-05-01 Report Number : FAA-AM-80-10;DOT/FAA/AM-80/10; URL : /view/dot/21238 "Changes in the oxygen-hemoglobin" (1980). "Changes in the oxygen-hemoglobin dissociation curve and time of useful function at hypobaric pressures in rats after chronic oral administration of propranolol." (1980) "Changes in the oxygen-hemoglobin dissociation curve and time of useful function at hypobaric pressures in rats after chronic oral administration of propranolol." , 1980 Export RIS Citation Information.

:

McKenzie, J.M. ;

Higgins, E.A.

1980-05-01

:

Twenty rats were given propranolol, 1.8 mg/kg body weight, by mouth for 12 days. On day 13, these and 20 control rats were tested for time of useful f...
Development of electrophysiological indices of neurological toxicity for organophosphate pesticides and depressant drugs.

CITE Title : Development of electrophysiological indices of neurological toxicity for organophosphate pesticides and depressant drugs. Creator(s) : Revzin, A.M. Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1979-05-01 Report Number : FAA-AM-79-15;DOT/FAA/AM-79/15; URL : /view/dot/21166 "Development of electrophysiological indices" (1979). "Development of electrophysiological indices of neurological toxicity for organophosphate pesticides and depressant drugs." (1979) "Development of electrophysiological indices of neurological toxicity for organophosphate pesticides and depressant drugs." , 1979 Export RIS Citation Information.

:

Revzin, A.M.

1979-05-01

:

Accurate control of eye movements and rapid detection of unexpected events in the periphery of the visual field are critically important in the aviati...
Effects of propranolol on time of useful function (TUF) in rats.

CITE Title : Effects of propranolol on time of useful function (TUF) in rats. Creator(s) : Higgins, E.A.;McKenzie, J.M.;Funkhouser, G.E.;Mullen, S.R.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1979-02-01 Report Number : FAA-AM-79-10;DOT/FAA/AM-79/10; URL : /view/dot/21161 "Effects of propranolol on" (1979). "Effects of propranolol on time of useful function (TUF) in rats." (1979) "Effects of propranolol on time of useful function (TUF) in rats." , 1979 Export RIS Citation Information.

:

Higgins, E.A. ;

McKenzie, J.M.

1979-02-01

:

To assess the effects of propranolol on tolerance to rapid decompression, a series of experiments was conducted measuring time of useful function (TUF...
The effects of altitude and two decongestant-antihistamine preparations on physiological functions and performance.

CITE Title : The effects of altitude and two decongestant-antihistamine preparations on physiological functions and performance. Creator(s) : Higgins, E.A.;Chiles, W.D.;McKenzie, J.M.;Jennings, A.E.;Funkhouser, G.E.;Mullen, S.R.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1978-04-01 Report Number : FAA-AM-78-19;DOT/FAA/AM-78/19; URL : /view/dot/21129 "The effects of altitude" (1978). "The effects of altitude and two decongestant-antihistamine preparations on physiological functions and performance." (1978) "The effects of altitude and two decongestant-antihistamine preparations on physiological functions and performance." , 1978 Export RIS Citation Information.

:

Higgins, E.A. ;

Chiles, W.D.

1978-04-01

:

Fourteen men were studied to determine the combined effects of two altitudes (ground level (1,274 ft) and 12,500 ft), and three preparations (lactose ...
Cardiorespiratory assessment of decongestant-antihistamine effects of altitude, +Gz, and fatigue tolerances.

CITE Title : Cardiorespiratory assessment of decongestant-antihistamine effects of altitude, +Gz, and fatigue tolerances. Creator(s) : Lategola, Michael T.;Davis, Audie W.;Lyne, Peggy J.;Burr, Mary J.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1978-04-01 Report Number : FAA-AM-78-20;DOT/FAA/AM-78/20; URL : /view/dot/21130 "Cardiorespiratory assessment of decongestant-antihistamine" (1978). "Cardiorespiratory assessment of decongestant-antihistamine effects of altitude, +Gz, and fatigue tolerances." (1978) "Cardiorespiratory assessment of decongestant-antihistamine effects of altitude, +Gz, and fatigue tolerances." , 1978 Export RIS Citation Information.

:

Lategola, Michael T. ;

Davis, Audie W.

1978-04-01

:

Decongestants and antihistamines are known to produce effects capable of adversely modifying physiological function and psychomotor task performance. ...
The role of monamine oxidase inhibition in the acute toxicity of chlordimeform.

CITE Title : The role of monamine oxidase inhibition in the acute toxicity of chlordimeform. Creator(s) : Smith, Paul W.;Robinson, Casey P.;Zelenski, Jane D.;Endecott, Boyd R.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1977-08-01 Report Number : FAA-AM-77-19;DOT/FAA/AM-77/19; URL : /view/dot/21112 "The role of monamine" (1977). "The role of monamine oxidase inhibition in the acute toxicity of chlordimeform." (1977) "The role of monamine oxidase inhibition in the acute toxicity of chlordimeform." , 1977 Export RIS Citation Information.

:

Smith, Paul W. ;

Robinson, Casey P.

1977-08-01

:

This paper presents data from experiments on male rats performed to determine whether drugs which interfere with central amine mechanisms would decrea...
Effects of lithium carbonate on performance and biomedical functions.

CITE Title : Effects of lithium carbonate on performance and biomedical functions. Creator(s) : Higgins, E.;Chiles, W.;McKenzie, J.;Davis, A.;Funkhouser, G.;Jennings, A.;Mullen, S.;Fowler, P.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1977-07-01 Report Number : FAA-AM-77-17;DOT/FAA/AM-77/17; URL : /view/dot/21110 "Effects of lithium carbonate" (1977). "Effects of lithium carbonate on performance and biomedical functions." (1977) "Effects of lithium carbonate on performance and biomedical functions." , 1977 Export RIS Citation Information.

:

Higgins, E. ;

Chiles, W.

1977-07-01

:

The effects of a single 600-mg dose of lithium carbonate were evaluated in a study of 15 healthy, normal male subjects. Subjects were studied, on two ...
Some effects of sleep deprivation on tracking performance in static and dynamic environments.

CITE Title : Some effects of sleep deprivation on tracking performance in static and dynamic environments. Creator(s) : Collins, William E. Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1976-01-01 Report Number : FAA-AM-76-12;DOT/FAA/AM-76/12; URL : /view/dot/21083 "Some effects of sleep" (1976). "Some effects of sleep deprivation on tracking performance in static and dynamic environments." (1976) "Some effects of sleep deprivation on tracking performance in static and dynamic environments." , 1976 Export RIS Citation Information.

:

Collins, William E.

1976-01-01

:

The influence of approximately 34 and 55 h of sleep deprivation on performance scores derived from manually tracking the localizer needle on an aircra...
The effects of dextroamphetamine on physiological responses and complex performance during sleep loss.

CITE Title : The effects of dextroamphetamine on physiological responses and complex performance during sleep loss. Creator(s) : Higgins, E.A.;Chiles, W.D.;McKenzie, J.M.;Iampietro, P.F.;Vaughan, J.A.;Funkhouser, G.E.;Burr, M.J.;Jennings, A.E.;West, G.; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1975-11-01 Report Number : FAA-AM-75-14;DOT/FAA/AM-75/14; URL : /view/dot/21072 "The effects of dextroamphetamine" (1975). "The effects of dextroamphetamine on physiological responses and complex performance during sleep loss." (1975) "The effects of dextroamphetamine on physiological responses and complex performance during sleep loss." , 1975 Export RIS Citation Information.

:

Higgins, E.A. ;

Chiles, W.D.

1975-11-01

:

On two separate occasions, performance of 10 male subjects was measured on the Civil Aeromedical Institute Multiple Task Performance Battery at 4-hour...
Interaction between marihuana and altitude on a complex behavioral task in baboons.

CITE Title : Interaction between marihuana and altitude on a complex behavioral task in baboons. Creator(s) : Lewis, Mark F.;Ferraro, Douglas Peter;Mertens, Henry W.;Steen, Jo Ann; Corporate Creator(s) : Civil Aeromedical Institute Corporate Contributor(s) : United States. Office of Aviation Medicine Published Date : 1975-01-01 Report Number : FAA-AM-75-6;DOT/FAA/AM-75/6; URL : /view/dot/21064 "Interaction between marihuana and" (1975). "Interaction between marihuana and altitude on a complex behavioral task in baboons." (1975) "Interaction between marihuana and altitude on a complex behavioral task in baboons." , 1975 Export RIS Citation Information.

:

Lewis, Mark F. ;

Ferraro, Douglas Peter

1975-01-01

:

Marihuana, or its principal active ingredient, delta-9-tetrahydrocannabinol (delta9-THC), impairs performance on complex behavioral tasks in animals a...

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