Effects of an organophosphorus pesticide on reproduction in the rat.

Details

• Creators:
  Ryan, Leonard C. ; Endecott, Boyd R. ; Hanneman, Gerald D. ; Smith, Paul W.
• Corporate Contributors:
  United States. Office of Aviation Medicine
• Subject/TRT Terms:
  • Aviation medicine
  • Insecticides
  • Esters
  • Phosphorus
  • Pesticides
  • Rats
  • Laboratory animals
  • Reproduction (Biology)
  • Brain
  • Physiological aspects
  More +
• Publication/ Report Number:
  AM 70-3 ; DOT/FAA/AM-70/3
• Resource Type:
  Tech Report
• Geographical Coverage:
  United States
• Corporate Publisher:
  Civil Aerospace Medical Institute
• Abstract:
  The toxic effects of organophosphorus insecticides are commonly ascribed to cholinesterase (CHE) inhibition. A search of the scientific literature revealed the well-established fact that a number of chlorinated pesticides adversely affect reproduction in mice and rats. ; However, little is known about the effects of organophosphorus pesticides on reproduction. Disulfoton was selected for this study because it is a widely used organophosphorus insecticide for which the acutely toxic, nonlethal dose in rats has been established.
• Format:
  PDF
• Download URL:
  https://rosap.ntl.bts.gov/view/dot/20892/dot_20892_DS1.pdf
• File Type:
  [PDF - 263.63 KB]
• Collection(s):
  FAA Civil Aerospace Medical Institute ; US Transportation Collection
• Main Document Checksum:
  urn:sha-512:b1dc0796fd72800b014876bbd9960dd2d4fd9dd854eaa71e6d22a28934e0b6b906b99d731cdab8082d997e70be6dc8ac634f5bf1517888910f3da005845fe316