Effects of an organophosphorus pesticide on reproduction in the rat.

Ryan, Leonard C.; Endecott, Boyd R.; Hanneman, Gerald D.; Smith, Paul W.

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Effects of an organophosphorus pesticide on reproduction in the rat.

1970-01-01
By Ryan, Leonard C. ; Endecott, Boyd R. ; Hanneman, Gerald D. ; ...

[PDF-263.63 KB]

English

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Creators:

Ryan, Leonard C. ; Endecott, Boyd R. ; Hanneman, Gerald D. ; Smith, Paul W.

Ryan, Leonard C. ; Endecott, Boyd R. ; Hanneman, Gerald D. ; Smith, Paul W. Less -
Corporate Contributors:

United States. Office of Aviation Medicine
Subject/TRT Terms:

[+]

Aviation Medicine Brain Cholinesterases Esters Insecticides Insecticides--Physiological Effect Laboratory Animals Organophosphorus Compounds Pesticides Pesticides--Physiological Effect Phosphorus Physiological Aspects Rats Rats As Laboratory Animals Reproduction Reproduction (Biology)
Publication/ Report Number:

AM 70-3 ; DOT/FAA/AM-70/3

AM 70-3 ; DOT/FAA/AM-70/3 Less -
Resource Type:

Tech Report
Geographical Coverage:

United States
Corporate Publisher:

Civil Aerospace Medical Institute
Abstract:

The toxic effects of organophosphorus insecticides are commonly ascribed to cholinesterase (CHE) inhibition. A search of the scientific literature revealed the well-established fact that a number of chlorinated pesticides adversely affect reproduction in mice and rats.

However, little is known about the effects of organophosphorus pesticides on reproduction. Disulfoton was selected for this study because it is a widely used organophosphorus insecticide for which the acutely toxic, nonlethal dose in rats has been established.
Format:

PDF
Collection(s):

FAA Civil Aerospace Medical Institute US Transportation Collection
Main Document Checksum:

[+]

urn:sha256:273901a5c42be9ead5945c803d1089eaf1fb8a7f2f397c6be694ed0b2b2cddc2
Download URL:

https://rosap.ntl.bts.gov/view/dot/20892/dot_20892_DS1.pdf
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Effects of an organophosphorus pesticide on reproduction in the rat.

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