Review of SSRI Cases to Assess Potential for Cognitive Decline
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2024-05-01
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Abstract:This study investigated the impact of selective serotonin reuptake inhibitor (SSRI) use on the cognitive performance of pilots, aiming to assess the necessity and frequency of neurocognitive evaluations mandated by current aeromedical guidelines. This study was conducted among medically-certificated airmen with a psychiatric diagnosis that were previously approved for SSRI use and subsequently applied for a new medical certificate between October 2019 and January 2022. Utilizing data from medically-certificated airmen with psychiatric diagnoses and approved SSRI use, the study examined variables such as age, SSRI type, psychiatric diagnoses, cognitive tests, and comorbidities. The analysis employed logistic regression to determine associations with abnormal cognitive outcomes measured by CogScreen testing.
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