Inhalation Toxicology: I. Design of a Small-Animal Test System; [and, Inhalation Toxicology:] II. Determination of the Relative Toxic Hazards of 75 Aircraft Cabin Materials

Crane, Charles R.; Sanders, Donald C.; Endecott, Boyd R.; Abbott, John K.; Smith, Paul W.; Civil Aeromedical Institute

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ROSA P serves as an archival repository of USDOT-published products including scientific findings, journal articles, guidelines, recommendations, or other information authored or co-authored by USDOT or funded partners. As a repository, ROSA P retains documents in their original published format to ensure public access to scientific information.

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Inhalation Toxicology: I. Design of a Small-Animal Test System; [and, Inhalation Toxicology:] II. Determination of the Relative Toxic Hazards of 75 Aircraft Cabin Materials

1977-01-01
By Crane, Charles R. ; Sanders, Donald C. ; Endecott, Boyd R. ; ...

[PDF-1.96 MB]

English

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Creators:

Crane, Charles R. ; Sanders, Donald C. ; Endecott, Boyd R. ; Abbott, John K. ; Smith, Paul W.

Crane, Charles R. ; Sanders, Donald C. ; Endecott, Boyd R. ; Abbott, John K. ; Smith, Paul W. Less -
Corporate Creators:

Civil Aeromedical Institute
Corporate Contributors:

United States. Office of Aviation Medicine
Subject/TRT Terms:

[+]

Aircraft Accidents Aircraft Cabins Aircraft Materials Air Transportation Crashes Combustion Deposits Combustion Gases--Toxicology Fatalities Gas Analysis Gases, Asphyxiating And Poisonous--Toxicology Laboratory Animals Laboratory Tests Poisons Poisons--Physiological Effect Polymers Pyrolysis Rats Rats As Laboratory Animals Smoke Thermal Degradation Toxicology
Publication/ Report Number:

FAA-AM-77-9 ; DOT/FAA/AM-77/9

FAA-AM-77-9 ; DOT/FAA/AM-77/9 Less -
Resource Type:

Tech Report
Geographical Coverage:

United States
Edition:

OAM report.
Corporate Publisher:

Civil Aerospace Medical Institute
Abstract:

In an effort to further the cause of increased safety for those who ride in commercial aircraft, this paper presents a detailed description of the genesis of a small-scale, laboratory test system that utilizes small animals to evaluate the relative toxic hazard of combustion products generated by the thermal decomposition of nonmetallic materials. It includes:

1. a discussion of the concepts that led to the design;

2. detailed instructions for fabricating the system;

3. operating parameters and instructions for conducting a test;

4. an evaluation of the system's performance as determined by the testing of 75 aircraft cabin materials;

5. the utilization of animal response time as a basis for expressing relative toxicity;

6. and a discussion of the derivation of an inhalation dose concept that promises to be more useful than lethal concentrations.
Format:

PDF
Collection(s):

FAA Civil Aerospace Medical Institute US Transportation Collection
Main Document Checksum:

[+]

urn:sha256:8c509018183473255ebb96b605ef2f80ef2b261a8f68d375cdab9d645743e56c
Download URL:

https://rosap.ntl.bts.gov/view/dot/21102/dot_21102_DS1.pdf
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Inhalation Toxicology: I. Design of a Small-Animal Test System; [and, Inhalation Toxicology:] II. Determination of the Relative Toxic Hazards of 75 Aircraft Cabin Materials

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