Inhalation Toxicology: I. Design of a Small-Animal Test System; [and, Inhalation Toxicology:] II. Determination of the Relative Toxic Hazards of 75 Aircraft Cabin Materials
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Subject/TRT Terms:
- Air transportation crashes
- Smoke
- Aircraft cabins
- Aircraft materials
- Poisons
- Polymers
- Combustion deposits
- Gas analysis
- Thermal degradation
- Toxicology
- Pyrolysis
- Fatalities
- Laboratory tests
- Laboratory animals
- Rats
- Aircraft accidents
- Aircraft cabins
- Poisons--Physiological effect
- Gases, Asphyxiating and poisonous--Toxicology
- Polymers
- Combustion gases--Toxicology
- Pyrolysis
- Rats as laboratory animals
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Edition:OAM report.
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Description:In an effort to further the cause of increased safety for those who ride in commercial aircraft, this paper presents a detailed description of the genesis of a small-scale, laboratory test system that utilizes small animals to evaluate the relative toxic hazard of combustion products generated by the thermal decomposition of nonmetallic materials. It includes:
1. a discussion of the concepts that led to the design;
2. detailed instructions for fabricating the system;
3. operating parameters and instructions for conducting a test;
4. an evaluation of the system's performance as determined by the testing of 75 aircraft cabin materials;
5. the utilization of animal response time as a basis for expressing relative toxicity;
6. and a discussion of the derivation of an inhalation dose concept that promises to be more useful than lethal concentrations. -
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