Effects of two antihistamine-containing compunds upon performance at three altitudes.

Higgins, E. Arnold; Davis, Audie W.; Fiorica, Vincent; Iampietro, P.F.; Vaughan, John A.; Funkhouser, Gordon E.; United States. Office of Aviation Medicine

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Effects of two antihistamine-containing compunds upon performance at three altitudes.

1968-06-01
By Higgins, E. Arnold ; Davis, Audie W. ; Fiorica, Vincent ; ...

[PDF-1.57 MB]

English

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Creators:

Higgins, E. Arnold ; Davis, Audie W. ; Fiorica, Vincent ; Iampietro, P.F. ; Vaughan, John A. ; ... More +

Higgins, E. Arnold ; Davis, Audie W. ; Fiorica, Vincent ; Iampietro, P.F. ; Vaughan, John A. ; Funkhouser, Gordon E. Less -
Corporate Creators:

United States. Office of Aviation Medicine
Subject/TRT Terms:

[+]

Air Pilots Altitude Altitudes Amines Antihistamines Blood--Analysis Blood Analysis Body Temperature Catecholamines Drug Effects Drugs--Physiological Effect Experiments Heart Beat Heart Rate Human Subject Testing Motor Ability Motor Skills Oxygen Performance Performance Tests Physiological Aspects Placebos Placebos (Medicine) Temperature Vasoconstrictors
Publication/ Report Number:

AM 68-15 ; DOT/FAA/AM-68/15

AM 68-15 ; DOT/FAA/AM-68/15 Less -
Resource Type:

Tech Report
Geographical Coverage:

United States
Corporate Publisher:

Civil Aerospace Medical Institute
Abstract:

In a study of 45 human subjects it was determined that a compound drug containing the antihistamine phenindamine did not statistically impair performance on a modified Mashburn coordinator. Another compound containing the antihistamine chlorpheniramine did impair performance. Performance was also impaired by increasing altitudes. The combined effects of the chlorpheniramine compound and increased altitude proved more detrimental to performance than the sum of the decrements that each influence caused when encountered separately. Although no significant performance decrement resulted from the administration of the phenindamine compound, undesirable side-effects were noted.
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PDF
Collection(s):

FAA Civil Aerospace Medical Institute US Transportation Collection
Main Document Checksum:

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urn:sha256:24c2a6f6f0902ff2607d02128691e395c750e6166b500910c0f7fcf0adf4ae02
Download URL:

https://rosap.ntl.bts.gov/view/dot/20854/dot_20854_DS1.pdf
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Effects of two antihistamine-containing compunds upon performance at three altitudes.

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