Distribution of Paroxetine in Postmortem Fluids and Tissues

Details

• Creators:
  Lewis, Russell J. ; Kemp, Philip M. ; Johnson, Robert D.
• Corporate Creators:
  United States. Department of Transportation. Federal Aviation Administration. Office of Aviation. Civil Aerospace Medical Institute
• Corporate Contributors:
  United States. Department of Transportation. Federal Aviation Administration. Office of Aviation. Office of Aerospace Medicine
• Subject/TRT Terms:
  • Air pilots
  • Air transportation crashes
  • Blood analysis
  • Drugs
  • Fatalities
  • Forensic medicine
  • Forensic toxicology
  • Paroxetine
  • Gas chromatograph/mass spectrometer (GC/MS)
  • Postmortem distribution
• Publication/ Report Number:
  DOT/FAA/AM-15/11
• Resource Type:
  Tech Report
• Geographical Coverage:
  United States
• Edition:
  Final Report
• Corporate Publisher:
  United States. Department of Transportation. Federal Aviation Administration. Office of Aviation. Civil Aerospace Medical Institute
• Abstract:
  Paroxetine is a selective serotonin reuptake inhibitor that is a commonly prescribed drug for the treatment of depression, obsessive-compulsive disorder, panic disorder, social anxiety disorder, premenstrual dysphoric disorder, and post-traumatic stress disorder. There are certain side effects associated with paroxetine use that could negatively affect a pilot's performance and become a factor in an aviation accident. Such side effects include nausea, drowsiness, insomnia, and dizziness. It has also been suggested that paroxetine use may increase suicidal behavior and suicidal ideation.
• Format:
  PDF
• Download URL:
  https://rosap.ntl.bts.gov/view/dot/57174/dot_57174_DS1.pdf
• File Type:
  [PDF - 384.54 KB]
• Collection(s):
  FAA Civil Aerospace Medical Institute
• Main Document Checksum:
  urn:sha256:35e9e20937a3ab74931d18bca5b40ad43b33b97a4180e95feb627ad1f61782e3