Biological inflammatory and metabolic effects of petro- and bio-diesel exhaust particulate matter emissions from a light-duty diesel engine.
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.

Search our Collections & Repository

For very narrow results

When looking for a specific result

Best used for discovery & interchangable words

Recommended to be used in conjunction with other fields

Dates

to

Document Data
Library
People
Clear All
Clear All

For additional assistance using the Custom Query please check out our Help Page

i

Biological inflammatory and metabolic effects of petro- and bio-diesel exhaust particulate matter emissions from a light-duty diesel engine.

Filetype[PDF-471.63 KB]


English
Details You May Also Like

Details:

  • Creators:
  • Corporate Creators:
    University of Vermont. Transportation Research Center
  • Corporate Contributors:
    United States. Dept. of Transportation
  • Subject/TRT Terms:
  • Publication/ Report Number:
    TRC Report # 15-009
  • Resource Type:
    Tech Report
  • Geographical Coverage:
    Vermont
  • Corporate Publisher:
    University of Vermont. Transportation Research Center
  • Abstract:
    Sustainability of our transportation system depends on making well-informed choices on

    vehicle energy sources for human and goods mobility. Motor vehicles operating on fossil

    fuels are a significant source of air pollution risk and challenge the ability of humans to

    mitigate climate change. Biodiesel is a low carbon fuel substitute for petroleum diesel,

    but relatively little is known about how exposure to biodiesel combustion particles affects

    chronic diseases such as asthma and type II diabetes mellitus (T2DM). This study

    examined the effect of particulate matter (PM) generated by the combustion of

    commercially available petrodiesel and soybean biodiesel fuels on inflammation and

    metabolic dysfunction using two types of in vivo experiments. To evaluate inflammation

    response, oropharyngeal 3-day exposures of females to B20 (20% biodiesel/80%

    petrodiesel by volume) and B0 (100% petrodiesel) particles from a light-duty diesel

    engine operating on a semi-transient cycle were followed by lung fluid and tissue

    biochemical analysis. Prenatal exposure effects on offspring growth and metabolism were

    evaluated by maternal exposure during gestational days 9-17 (delivery 18-20 days) and

    monitoring offspring for 12 months. Prenatal exposure to exhaust PM from petrodiesel

    fuel combustion had different metabolic effects in male vs. female offspring. For B20

    exhaust PM, the number of offspring was too low to detect differences. The results of this

    study suggest that males and females may have differential risk for metabolic dysfunction

    after prenatal exposure during gestation. Future studies should be conducted to quantify

    sex-specific effects on exposure to vehicle exhaust PM from biodiesel fuel blends.

  • Format:
    PDF
  • Collection(s):
  • Main Document Checksum:
  • Download URL:
  • File Type:

Supporting Files

  • No Additional Files
More +

You May Also Like

Checkout today's featured content at rosap.ntl.bts.gov