Acute and chronic effects of the insecticide endrin on renal function and renal hemodynamics.

Reins, D.A.; Holmes, D.D.; Hinshaw, L.B.; Civil Aeromedical Research Institute. Aeronautical Center

Advanced Search

Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.

Search our Collections & Repository

Advanced Search
Custom Query

All these words:

For very narrow results

This exact word or phrase:

When looking for a specific result

Any of these words:

Best used for discovery & interchangable words

None of these words:

Recommended to be used in conjunction with other fields

Language:

Dates

Publication Date Range:

to

Document Data

Title:

Document Type:

Library

Collection:

Series:

People

Author:

Clear All

Query Builder

Query box

Clear All

For additional assistance using the Custom Query please check out our Help Page

i

Acute and chronic effects of the insecticide endrin on renal function and renal hemodynamics.

1963-10-01
By Reins, D.A. ; Holmes, D.D. ; Hinshaw, L.B.

[PDF-419.12 KB]

English

Details You May Also Like

Details:

Creators:

Reins, D.A. ; Holmes, D.D. ; Hinshaw, L.B.

Reins, D.A. ; Holmes, D.D. ; Hinshaw, L.B. Less -
Corporate Creators:

Civil Aeromedical Research Institute. Aeronautical Center
Subject/TRT Terms:

[+]

Abdomen Adrenal Glands Air Pilots Blood--Analysis Blood-vessels--Dilatation Blood Analysis Brain Chlorine Organic Compounds Chlorohydrocarbons Creatinine Deglutition Disorders Dogs Dogs As Laboratory Animals Endrin--Physiological Effect Glomerular Filtration Rate Heart Hemodynamics Hydrocarbons Hypertension Insecticides Internal Organs Intestines Kidney Function Tests Laboratory Animals Liver Lungs Medical Examinations And Tests Pancreas Pathology Pesticides Photometers Photometry Poisons Potassium Renal Artery Renal Circulation Renal Hypertension Sodium Spinal Column Spleen Sympathomimetic Agents Urine
Publication/ Report Number:

AM 63-26 ; DOT/FAA/AM-63/26

AM 63-26 ; DOT/FAA/AM-63/26 Less -
Resource Type:

Tech Report
Geographical Coverage:

United States
Corporate Publisher:

Civil Aerospace Medical Institute
Abstract:

Chronic and acute effects of the insecticide endrin on renal function were studied in dogs. Animals were exposed to endrin chronically by intramuscular injection and acutely by intravenous infusion. In acute studies dogs developed systemic hypertension and increased renal vascular resistance attributable to a sympatho-adrenal action.

Basic renal autoregulation was not impaired by endrin but was masked by effects of blood borne adrenergic agents. Changes in renal function were minimal. In chronic studies dogs developed progressive systemic hypotension with variable changes in renal function and terminal renal vasodilation in some instances. Pathological findings were minimal and could be related to hemodynamic alteration in the peripheral vasculature.

Results from this investigation provide no evidence for renal failure due to chronic insecticide poisoning.
Format:

PDF
Collection(s):

FAA Civil Aerospace Medical Institute US Transportation Collection
Main Document Checksum:

[+]

urn:sha256:481e8c4ab01db4eef3fc338fc7aa4295ec8d297b8f4a332c2c62ddc3f392489e
Download URL:

https://rosap.ntl.bts.gov/view/dot/20876/dot_20876_DS1.pdf
File Type:

No Additional Files

More +

Acute and chronic effects of the insecticide endrin on renal function and renal hemodynamics.

Details:

Supporting Files

You May Also Like