Pupillary movements during acute and chronic fatigue : a new test for the objective evaluation of tiredness.

Lowenstein, Otto; Feinberg, Richard; Loewefeld, Irene E.; Columbia University. College of Physicians and Surgeons; Georgetown Clinical Research Institute

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Pupillary movements during acute and chronic fatigue : a new test for the objective evaluation of tiredness.

1963-04-01
By Lowenstein, Otto ; Feinberg, Richard ; Loewefeld, Irene E.

[PDF-1.08 MB]

English

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Creators:

Lowenstein, Otto ; Feinberg, Richard ; Loewefeld, Irene E.

Lowenstein, Otto ; Feinberg, Richard ; Loewefeld, Irene E. Less -
Corporate Creators:

Columbia University. College of Physicians and Surgeons ; Georgetown Clinical Research Institute

Columbia University. College of Physicians and Surgeons ; Georgetown Clinical Research Institute Less -
Subject/TRT Terms:

[+]

Age Alertness Brain Case Studies Central Nervous System Drowsiness Drug Effects Drugs--Physiological Effect Experiments Eye Eye Movements Fatigue Fatigue (Physiological Condition) Human Subject Testing Mydriatics Nerves Nervous System Nervous System Diseases Night Vision Oscillations Pathology Physiological Aspects Pupil (Eye) Pupillometry Reaction Time Reflexes--Testing Sleep Sphincters Vision
Publication/ Report Number:

AM 65-9 ; DOT/FAA/AM-65/9

AM 65-9 ; DOT/FAA/AM-65/9 Less -
Resource Type:

Tech Report
Geographical Coverage:

United States
Corporate Publisher:

Civil Aerospace Medical Institute
Abstract:

Spontaneous pupillary movements in darkness were recorded in

1.healthy subjects of different ages when they were rested or fatigued,

2.chronically tired subjects without known neurological defects, and

3.patients with various neurological lesions.

In some of the experiments, local or systemic drugs were used. While the pupils are large and quiet in darkness when the subject is alert, they oscillate under the influence of tiredness. Waves of spontaneous pupillary contraction and dilation accompany periods of increasing sleepiness and spontaneous arousal until, at the moment immediately preceding sleep, the pupils become very small. The mechanism of these movements was analyzed and a simple test described which allows the objective determination of the degree of acute fatigue in a given subject at a given time. In the light of these results, the concepts of 'normal' and of 'pathologic' fatigue were discussed.
Format:

PDF
Collection(s):

FAA Civil Aerospace Medical Institute US Transportation Collection
Main Document Checksum:

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urn:sha256:3ddcfe865cfbed8022d5954d4ebb714eaf551d5436e6fece49de6f5dfaed03f1
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https://rosap.ntl.bts.gov/view/dot/20737/dot_20737_DS1.pdf
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Pupillary movements during acute and chronic fatigue : a new test for the objective evaluation of tiredness.

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