United States Department of Transportation
i
Transient Global Amnesia and Aeromedical Certification: Literature Review
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2018-10-01
[PDF-260.34 KB]
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Edition:Final
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Abstract:Transient Global Amnesia (TGA) is a rare clinical syndrome of anterograde amnesia with potentially disastrous consequences should it occur to a pilot inflight. Since 1958, multiple investigations have been carried out with the objective of determining its etiology and long-term prognosis. Migraine, focal ischemia, venous flow abnormalities, epileptic phenomena, and personality traits have all been implicated as potential etiologic factors; however, there is no current consensus on the cause. TGA generally has a benign prognosis with a low recurrence rate, nevertheless, an acute episode of TGA presents an unacceptable risk of sudden incapacitation in flight. This unacceptable risk creates the need to familiarize aviation medicine practitioners with this condition and its pathophysiology. This paper summarizes the long-term prognosis of TGA, the long-term outcome for an airman experiencing this condition more than once, the long-term limitation(s) and neurological conditions associated with TGA, and the waiting period established by the FAA in consideration of an aeromedical certification applicant with this condition.
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