Sensitivity of some tests for alcohol abuse : findings in nonalcoholics recovering from intoxication.

McKenzie, J.M.; Higgins, E.A.; Fowler, P.R.; Funkhouser, G.E.; White, M.A.; Moser, E.; Civil Aeromedical Institute

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Sensitivity of some tests for alcohol abuse : findings in nonalcoholics recovering from intoxication.

1983-01-01
By McKenzie, J.M. ; Higgins, E.A. ; Fowler, P.R. ; ...

[PDF-900.22 KB]

English

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Creators:

McKenzie, J.M. ; Higgins, E.A. ; Fowler, P.R. ; Funkhouser, G.E. ; White, M.A. ; ... More +

McKenzie, J.M. ; Higgins, E.A. ; Fowler, P.R. ; Funkhouser, G.E. ; White, M.A. ; Moser, E. Less -
Corporate Creators:

Civil Aeromedical Institute
Corporate Contributors:

United States. Office of Aviation Medicine
Subject/TRT Terms:

[+]

Air Pilots Air Pilots--Alcohol Use--Physiological Aspects Alcohol Abuse Alcoholism Amines Blood Alcohol--Analysis Blood Alcohol Levels Blood Pressure Catecholamines Experiments Heart Beat Heart Rate Human Subject Testing Intoxication Performance--Testing Performance Tests Urinalysis Urine--Analysis
Publication/ Report Number:

FAA-AM-83-2 ; DOT/FAA/AM-83/2

FAA-AM-83-2 ; DOT/FAA/AM-83/2 Less -
Resource Type:

Tech Report
Geographical Coverage:

United States
Edition:

OAM report.
Corporate Publisher:

Civil Aerospace Medical Institute
Abstract:

A variety of measurements are sensitive to alcoholism; some may be applicable to screening programs, but more precise knowledge of sensitivity and specificity would help to select a minimal test battery. This study assessed the sensitivity of some tests for alcoholism to a single drinking episode.

Fifteen nonalcoholic men, 26-59 years old, participated. On one evening they drank ethonal, raising their blood alcohol concentrations (BAC's) to 100-200 mg/dl for at least 2h. At 0700 on the next morning, after 7 h of sleep, they ate breakfast, then completed a battery of performance tests. Blood samples were drawn at 0730 and 1130.

The effects of alcohol, estimated by comparison of data with those obtained on another morning of the same week after an evening of abstinence, are summarized: Heart rate, during sleep and all the next morning, was higher; blood pressure, at 0700 and 1100, was unaffected. There was no effect on core body temperature, recorded hourly from 2400. The urinary excretion rates of catecholamines and ketogenic adrenal steroids were augmented by alcohol. The drug did not affect blood levels of gamma-glutamyl transpeptidase, glutamate oxaloacetate transaminase, high density lipid or total cholesterol, or uric acid.

Performance tests affected by alcohol were number comparison, number addition, analysis of complex statements, and adaptability (from an air traffic controller selection batter). Tests not affected were abstract reasoning, digit code, digit symbol, short-term memory, hand steadiness, pursuit tracking, rod-and-frame, and 100-hue color sorting.
Format:

PDF
Collection(s):

FAA Civil Aerospace Medical Institute US Transportation Collection
Main Document Checksum:

[+]

urn:sha256:48d1e1eb45043ffd1c9c5a140d397e7e71716424ee7e624480ad9f98808cb415
Download URL:

https://rosap.ntl.bts.gov/view/dot/21228/dot_21228_DS1.pdf
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Sensitivity of some tests for alcohol abuse : findings in nonalcoholics recovering from intoxication.

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